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Selected PoNG Publications

 

Genetics

Fan CC, Banks SJ, Thompson WK, Chen CH, McEvoy LK, Tan CH, Kukull W, Bennett DA, Farrer LA, Mayeux R, Schellenberg GD, Andreassen OA, Desikan R, Dale AM. (2020). Sex dependent autosomal effects on clinical progression of Alzheimer's Disease. Brain.

Krebs MD, Themudo GE, Benros ME, Werge T, Thompson WK (In Revision). Biological Predictors of Psychiatric Trajectories in a Danish Population Cohort of Individuals with Schizophrenia. Nature Communications.

Wang Y, Nudel R, Benros ME, Skogstrand K, Fishilevich S, iPSYCH-BROAD, Lancet D, Sun, Hougaard DM, Andreassen OA, Mortensen PB, Demur A, Hansen TF, Thompson WK, Werge T (2020). Genome-Wide Association Study Identifies 16 Genomic Regions Associated with Circulating Inflammatory Markers at Birth. PLoS Genetics.

Nudel R, Benros ME, Krebs MD, Allesøe RL, Lemvigh CK, Bybjerg-Grauholm J, Børglum A, Daly M, Nordentoft M, Mors O, Hougaard D, Mortensen PB, Buil A, Werge T, Rasmussen S, Thompson WK (2019). Immunity and mental illness: findings from a large Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders. European Journal of Human Genetics.

Fan CC, McGrath JJ, Appadurai V, Buil A, Gandal MJ, Schork AJ, Mortensen PB, Agerbo E, Geschwind SA, Geschwind D, Werge T, Thompson WK*, Pedersen CB (2018). Spatial gene-by-environment mapping for schizophrenia reveals locale of upbringing effects beyond urban-rural differences. Nature Communications. *co-senior authors.

Marty R, Thompson WK, Salem RM, Maurizio Zanetti M, Carter H (2018). Evolutionary pressure against MHC class II binding cancer mutations. Cell.

Schwartzman A,  Schork AJ,  Zablocki R,  Thompson WK (2018). A simple, consistent estimator of heritability for genome-wide association studies. Annals of Applied Statistics.

Schork AJ, Won H, Appadurai V, Nudel R, Gandal M, Delaneau O,  Hougaard D, Baekved-Hansen M, Bybjerg-Grauholm J, Pedersen MG, Pedersen CB, Neale BM, Daly MJ, Nordentoft M, Mors O, Boerglum AD,  Mortensen PB, Buil A, Thompson WK, Geschwind D, Werge T (2018). A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator. Nature Neuroscience.

Olsen L,  Sparsø T, Weinsheimer SM, Bertalan M, Mazin W, Rosengren A, Sanchez X, Hoeffding LK, Schmock H, Baekvad-Hansen M, Bybjerg-Grauholm J, Daly MJ, Neale BM, Pedersen MG, Agerbo E, Mors O, Børglum A, Nordentoft M, Hougaard DM, Mortensen PB, Geschwind DH, Pedersen CH, Thompson WK*, Werge T* (2018). Rearrangements in the 22q11.2 Region: Prevalence and Population-Based Risk for Neuropsychiatric and Developmental Disorders. Lancet Psychiatry. *co-senior authors.

Picart-Armada S, Thompson WK, Buil A, Perera-Lluna A (2017). An R package to compute diffusion-based scores on biological networks: diffusion. Bioinformatics.

Zablocki R, Levine R, Schork A, Wang Y, Thompson WK (2017). Semi-parametric covariate-modulated local false discovery rate for genome-wide association studies. Annals of Applied Statistics.

 

Imaging Analysis

Zhao W, Palmer CE, Thompson WK, Chaarani B, Garavan HP, Casey BJ, Jernigan TL, Dale AM, Fan CC*. (2020). Individual differences in cognitive performance are better predicted by global rather than localized BOLD activity patterns across the cortex. Cerebral Cortex (in press). * corresponding author

Rapuano KM, Laurent JS, Hagler DJ, Hatton SN, Thompson WK, Jernigan TL, Dale AM, Casey BJ, Watts R (2020). Nucleus Accumbens Cytoarchitecture Predicts Weight Gain in Children. Proceedings of the National Academy of Science.

Thompson WK, Barch D,  Bjork J, Gonzalez R, Nagel B, Nixon SJ, Luciana M (2019). The Structure of Cognition in 9 and 10 year-old Children and Associations with Problem Behaviors: Findings from the ABCD Study’s Baseline Neurocognitive Battery. DCN

Paulus MP and Thompson WK (2019). Computational approaches and machine learning for individual-level treatment predictions. Psychopharmacology: 1-9.

Paulus MP and Thompson WK (2019). The Challenges and Opportunities of Small Effects: The New Normal in Academic Psychiatry. Editorial, JAMA Psychiatry.

Ombao H, Lindquist M, Thompson WK, Aston J, editors (2016). Handbook of Neuroimaging Data Analysis. CRC Press.

Population Neuroscience and Genetics (PoNG) Lab